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KUBVUNZA ZVINOMamiriro ekufambisa & inokurudzirwa nzira yekutumira:
nemhepo, negungwa kana nekutaura
Mamiriro ekuchengetedza:
Ramba uri munzvimbo ine rima, Yakavharwa pakaoma, Kamuri Tembiricha
Minimum Order Qty:
Kukurukurirana
Certification:
COA, HPLC, GC, HNMR, Assay, Mvura Yemukati(KF), TLC iripo
dimethyl(tert-butoxycarbonyl) -D-glutamate;
(R) -2-tert-Butoxycarbonylamino-pentanedioic acid dimethyl ester;
(Tert-Butoxy)Carbonyl D-Glu(OMe)-OMe (Syrup);
Boc-D-Glu(OMe)-OMe (Syrup);
dimethyl (2R) -2- [(2-methylpropan-2-yl)oxycarbonylamino]pentanedioate;
Alogliptin Kusachena 43;
1,5-dimethyl (2R) -2 -[(tert-butoxy)carbonyl]amino}pentanedioate
Vanowanzo shandiswa kutakura hupfu.Uye vanogona kudzivirira kupenya kwezuva nemvura kuti zvisashata.
Iyo hard carton inogona kuchengetedza zvigadzirwa zvako kubva pakuputsika uye kunyorova.
Fluoroquinolones ine yakafara antibacterial spectrum, yakasimba antibacterial chiitiko, yakaderera yakashata maitiro, yakanaka matishu permeability, yakakwirira yemuromo bioavailability, nguva yakareba yekutonga uye kutonga kuri nyore.Ivo vanowanzoshandiswa mukurapa zvirwere zvinotapukira zvakadai sekufema turakiti chirwere uye urinary tract infection.Chimiro chefluoroquinolone antibacterial drugs chinoratidzwa nekuvapo kwefluorine munzvimbo yechitanhatu ye quinolone mubereki nucleus.
Zvisinei, mumakore gumi achangopfuura, nekuda kwekumanikidzwa kwakasarudzwa kunokonzerwa nekushandiswa kwakakura kwemhando iyi yemishonga, zvirwere zvisingagadziriswi nemishonga zvinowedzera, kunyanya mumakore achangopfuura, quinolone-resistant Streptococcus pneumoniae ine cross-resistance, iyo inopesana nepenicillin, macrolide antibiotics uye quinolone antibiotics.Panguva imwe chete, zvakaonekwa kuti mamwe fluoroquinolones anogona kukonzera QTc interval kurebesa electrocardiogram, hepatotoxicity uye phototoxicity, izvo zvishoma kushandisa kwavo.
Kuti ukunde zvikanganiso zviri pamusoro zvefluoroquinolones, zvinokasira kuumba makomisheni matsva ane yakanaka antibacterial chiitiko, yakakura antibacterial spectrum uye diki sezvinobvira maitiro akashata kurwisa mabhakitiriya anopesana nemishonga.Mutsara wemishonga mitsva yefluoroquinolone-isina (NFQ) ichangobva kugadzirwa ine 8-methoxyl yakasiyana nefluoroquinolone antibiotics pakuti haina fluorine panzvimbo yechitanhatu yequinolone mubereki nucleus, asi ichiri yakasimba in vitro antibacterial activity.nemonoxacin itsva NFQ inosarudza bhakitiriya topoisomerase inhibitor.
Kuenzaniswa neiyo fluoroquinolones pari zvino pamusika, Nenofloxacin inomiririra kirasi nyowani yemishonga yemaitiro.nemonocacin (TG-873870), mushonga mutsva wequinolone wakagadzirwa neProcter & Gamble (P&G), wakaratidza basa rakakosha reantibacterial kurwisa zvirwere zvakasiyana-siyana zvekiriniki, kusanganisira Staphylococcus aureus uye multidrug-resistant Streptococcus pneumoniae.Migumisiro yekuedza mumakonzo ane utachiona yakaratidza kuti antibacterial effect yechigadzirwa ichi yakanga yakasimba kudarika yakawanda yezvino quinolones.Mukuwedzera, chigadzirwa chacho chine yakanakisa pharmacokinetic properties uye inoshivirirwa zvakanaka.
Fmoc-Gly-glu(otbu)-oh | Boc-D-Glu(OBzl)-Oet |
HL-Glu-OH | Boc-D-Glu(Obzl)-OH |
HD-Glu-OH | Boc-D-Glu(Ome)-OH |
DL-Glu-OH | Boc-D-Glu(Ome)-OH.DCHA |
DL-Glu-OH.H2O | Boc-Glu(OBzl)-Obzl |
L-Glu(Obzl)-NCA | Boc-L-Glu-OBzl |
D-Glu(Obzl)-NCA | Boc-D-Glu-Obzl |
DL-Glu(Obzl)-NCA | Boc-D-Glu-Otbu-OH |
L-Glu-Obzl | Boc-D-Glu(OMe)-OMe |
Tos-Glu-Obzl | Boc-D-Glu(Obzl)-Obzl |
L-Glu(Ome)-Obzl.TOS | Boc-L-Glu(Ome)-Ome |
AC-Glu(OtBu) | Boc-L-Glu(OMe)-OH |
DL-Glu(Ome) | Boc-L-Glu(OBzl)-OH |
HD-Glu(OMe)-OH | Boc-Glu-Otbu |
HL-Glu(OMe)-OH | Boc-L-Glu(Obzl)-Ome |
L-Glu(Obzl) | Boc-L-Glu(Oet) |
HL-Glu(OtBu)-OH | Fmoc-L-Glu-OH |
HL-Glu(OEt)-OH | Fmoc-D-Glu-OH |
L-Glu(Otbu)-Otbu-OH | Fmoc-D-Glu(Ome)-OH |
HD-Glu(OBzl)-OH | Fmoc-L-Glu(OcHx)-OH |
D-Glu-OBzl | Fmoc-L-Glu(OMe)-OH |
HL-Glu(Ome)-Otbu.Hcl | Fmoc-L-Glu(OtBu)-OH |
D-Glu(Obzl)-Otbu.HCL | Fmoc-D-Glu(OBzl)-OH |
D-Glu(OtBu)-OtBu•HCl | Fmoc-D-Glu(Otbu)-OH |
L-Glu(OcHx).hcl | Fmoc-L-Glu-OtBu |
HL-Glu(OBzl)-OBzl.HCl | Fmoc-L-Glu(OBzl)-OH |
HL-Glu-OBzl.HCl | Fmoc-L-Glu(Cbz-hongu) |
D-Glu(OBzl)-OBzl.HCl | Fmoc-N-Me-L-Glu(Otbu)-OH |
DL-Glu(Ome)-Ome.Hcl | Fmoc-glu-obzl |
HL-Glu(OtBu)-OtBu•HCl | Cbz-L-Glu-OH |
HL-Glu(OMe)-OMe.HCl | Cbz-D-Glu-OH |
L-Glu(Obzl)-OME.HCL | ZL-Glu-OBzl |
HL-Glu(OEt)-OEt·HCl | ZD-Glu-OBzl |
L-Glu(Obzl)-Otbu.HCl | Cbz-L-Glu-Otbu |
HD-Glu(OMe)-OMe·HCl | Cbz-D-Glu(ome) |
N-Pht-Glu | Cbz-L-Glu(OBzl)-OH |
Boc-L-Glu-OH | Cbz-L-Glu(Otbu) |
Boc-D-Glu-OH | Cbz-L-Glu(Ome) |
Boc-Glu(obzl)-NH2 | Cbz-D-Glu(OtBu)-OH |
Boc-Glu (trt)-OH | Cbz-L-Glu(Ome)-OtBu |
Boc-L-Glu(OcHx)-OH | Cbz-L-Glu-OBzl.DCHA |
Boc-L-Glu(OtBu)-OH | Cbz-L-Glu(Oet)-OH |
Boc-Glu(Osu)-Otbu | Boc-Glu-Otbu (Osu) |
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