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FMOC-ALA-ALA-OH;
Fmoc-L-Ala-L-Ala-OH;
(S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanamido)propanoic acid;
Fmoc-Ala-Ala-OH99%;
FMoc-Ala-Ala;
FMOC-ALA-ALA-OH;
FMOC-L-ALANYL-L-ALANINE;
FMoc-AA-OH;
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-alanine
Vanowanzo shandiswa kutakura hupfu.Uye vanogona kudzivirira kupenya kwezuva nemvura kuti zvisashata.
Iyo hard carton inogona kuchengetedza zvigadzirwa zvako kubva pakuputsika uye kunyorova.
Ichi chigadzirwa i polypeptide inoumbwa ne28 amino acids.For N - acetyl - L - silk ammonia acyl - L - alpha amino ammonia acyl - L - propylene ammonia acyl - L - propylene ammonia acyl - L - valerian ammonia acyl - L - alpha amino ammonia acyl - L - Sue ammonia acyl - L wire ammonia acyl - L - wire ammonia acyl - L - alpha glutamine - L - different light ammonia acyl - L - Sue ammonia acyl - L - Sue ammonia acyl - L - lai ammonia acyl - L - alpha amino ammonia acyl - L - bright ammonia acyl - L - lai ammonia acyl - L - alpha - glutamine - L - lai ammonia acyl - L - alpha glutamine - L - valerian ammonia acyl - L - valerian ammonia acyl - L - alpha glutamine - L - alpha - glutamine - L - propylene ammonia waini - L - alpha - glutamine - L - asparagine.Maererano nekuverenga kweanhydrous uye acetic acid-isina chinhu, thymus ine nzira (C129 H215 N33O55) inofanira kuva 95.0% ~ 105.0%.
Ichi chigadzirwa chichena kana chichena poda kana kusununguka kwehuwandu.
Ichi chigadzirwa chinonyungudutswa mu trifluoroacetic acid, inonyungudika zvishoma mumvura, isingagadzirike muacetonitrile, ether uye trichloromethane.
Tora chigadzirwa ichi, chiyera nemazvo, wedzera 0.02mol/L phosphate buffer solution (pH 7.0)(tora 2.72g potassium dihydrogen phosphate, wedzera 0.1mol/L sodium hydroxide solution 116.4ml kunyungudusa, dilute nemvura kusvika pa1000ml) wogadzira a mhinduro ine inenge 5mg mu1ml yega yega.Zvichitemwa maererano nemutemo (Appendix ⅥE yeChikamu II chePharmacopoeia, 2010 edition), iyo chaiyo curl inofanira kuva -100.0 ° kusvika -110.0 ° zvichienderana nekuverenga kweanhydrous uye acetic-isina zvinhu.
Maitiro echiito chechigadzirwa ichi mukurapa chisingaperi hepatitis B uye kuwedzera immune system reactivity haina kunyatsojekeswa.Zvakawanda zvezviyedzo zve in vitro zvakaratidza kuti chigadzirwa ichi chinogona kukurudzira kukura kweT lymphocytes nekukurudzira mitogen yeperipheral blood lymphocytes, kuwedzera mazinga e interferon α, interferon γ, interleukin 2, interleukin 3 nezvimwe zvinhu zve lymphatic zvakavanzwa neT masero. mushure mekushandiswa kweantigen kana mitogen, uye panguva imwechete kuwedzera huwandu hwe lymphofactor receptors pamusoro peT masero.Inogona zvakare kuwedzera mhinduro yeallogeneic uye autologous yemunhu yakasanganiswa lymphocytes kuburikidza ne activation yeCD4 masero.Ichi chigadzirwa chinogona kuwedzera kuunganidzwa kwe-pre-NK masero, uye interferon inogona kuwedzera cytotoxicity yavo.In vivo zviedzo zvakaratidza kuti chigadzirwa ichi chinogona kuwedzera kutaura kweyero ye interleukin-2 receptor uye secretion level ye interleukin-2 mu mouse lymphocytes mushure me cancanadin A activation.
Gly-Ala-Ome.hcl | Fmoc-L-Ala-OH | β-Ala-Ome.HCl | L-Ala-Phe-OH |
Gly-Gly-Ala-Ome.hcl | Fmoc-DL-Ala | HL-Ala-Ome.Hcl | L-Ala-Leu-OH |
L-ALA | Fmoc-D-Ala-OH | β-Ala-Otbu.HCl | L-Ala-Pro-OH |
DL-ALA | Fmoc-β-Ala-OH | DL-Ala-Otbu.Hcl | DL-Ala-DL-Val |
H-Ala-ol | Fmoc-LN-Me-Ala-OH | L-Ala-NH2.HCl | Ala-Gly-Ome.hcl |
β-Ala-ol | Fmoc-N-Me-D-Ala-OH | HD-Ala-NH2·HCl | L-Ala-Ala-Obzl.HCl |
D-ALA | Fmoc-Ala-Cl | HD-Ala-NH2 | D-Ala-D-Ala-Ome.Hcl |
H-β-Ala-OH | Fmoc-L-Ala-Ol | Ac-L-Ala-NH2 | H-Ala-Ala-Otbu.HCL |
HN-Me-L-Ala-OH | fmoc-β-Ala-NH2 | Ac-D-Ala-NH2 | Boc-Ala-Phe-OH |
HN-Me-D-Ala-OH | Fmoc-Ala-Ome | AC-D,L-Ala-OH | Boc-L-Ala-Leu |
L-Ala-NCA | Fmoc-Ala-Osu | Ac-D-Ala-OH | Boc-ALA-Val-OH |
D-Ala-NCA | fmoc-β-Ala-osu | AC-L-Ala-OH | Boc-Ala-Pro |
L-Ala-nbu.hcl | Cbz-L-Ala-OH | AC-L-Ala-OME | Boc-Ala-Gly-OH |
L-Ala-Otbu | Cbz-D-Ala-OH | Pht-D-Ala | Boc-Ala-Ala-OH |
D-ALA-Oipr.HCL | Cbz-N-Me-L-Ala-OH | Pht-L-Ala | Boc-Ala-Ala-Ome |
D-Ala-Otbu.Hcl | Cbz-N-Me-D-Ala-OH | Boc-L-Ala-OH | Boc-Ala-Ala-Obzl |
N-Me-L-Ala-OMe | Cbz-DL-Ala-OH | Boc-D-Ala-OH | Fmoc-Ala-pro |
HD-Ala-OBzl·HCl | Z-β-L-Ala-OH | Boc-DL-Ala-OH | Fmoc-Ala-gly-OH |
β-Ala-Obzl.Tos | Cbz-L-Ala-OL | Boc-β-Ala-OH | Fmoc-L-Ala-Ala-OH |
H-Ala-OBzl·HCl | Cbz-L-Ala-NH2 | Boc-N-Me-Ala-OH | Fmoc-β-Ala-D-phe |
HL-Ala-OBzl.Tos-OH | Cbz-L-Ala-Ome | Boc-N-Me-DL-Ala-OH | Fmoc-β-Ala-D-Tyr (Et) |
HD-Ala-Oet.HCl | Cbz-D-Ala-OMe | Boc-N-Me-D-Ala-OH | Cbz-Ala-Val-OH |
HL-ALA-Oipr.HCL | Cbz-Beta-Ala-Ome | Boc-L-Ala-Ol | Cbz-L-Ala-Ala-OH |
N-Me-Ala-Otbu.Hcl | Cbz-β-Ala-Otbu | Boc-D-Ala-Ol | Cbz-Ala-Pro-OH |
HL-Ala-OtBu·HCl | Cbz-L-Ala-Osu | Boc-DL-Ala-Ol | Cbz-L-Ala-Leu-OH |
H-DL-Ala-OMe.HCl | Cbz-Beta-Ala-OSU | Boc-Ala-NH2 | Cbz-L-Ala-Ala-Ome |
β-Ala-Oet.HCl | Ala-Ala-OH | Boc-D-Ala-NH2 | Ala-Ala-Ome.HCL |
N-Me-L-Ala-Ome.hcl | Ala-gly | Boc-β-Ala-NH2 | Val-Ala |
HD-Ala-Ome.Hcl | L-ALA-Val-OH | Boc-D-4-Chloropheny(alanine) | Boc-Ala-Pro |
Boc-L-ALA-OBZL | Boc-Leu-Ala | Boc-D-3(1-Naphthgl)-alanine | Boc-Val-Ala |
Boc-L-Ala-OSu | Fmoc-leu-ala | Boc-L-Ala-Ome | Cbz-Val-Ala-OH |
Boc-L-Beta-Ala-Osu | Cbz-Leu-Ala-OH | Boc-D-Ala-OMe | Cbz-Val-Ala-Ome |
Boc-D-Ala-OSu | Phe-Ala | Boc-L-Ala-Otbu | Leu-Ala-OH |
Fmoc-L-Ala-OH.H2O | Boc-Phe-Ala-OH | Z-Lys(boc)-Ala-Ala-OBzl | HL-Thr-OBzl oxalate |
HL-Thr(Bzl)-OBzl.oxalate | Cbz-Phe-Ala-OH |
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